Introduction Current treatments for chronic pain (eg, opioids) can have adverse side effects and rarely result in resolution of pain.As such, there is a need for adjuvant analgesics that are non-addictive, have few adverse side effects and are effective for pain management across several chronic pain conditions.Oxytocin is a naturally occurring hor

Right ventricular (RV) mid-septal pacing should have fewer negative effects on left ventricular function compared to apical pacing.However, targeting the mid-septum may be technically challenging since it is usually done with two-dimensional fluoroscopy.The rotation of the heart and various shapes of the RV make it difficult to assess, whether the

Objective: The Vitamin D receptor (VDR) has been positively associated with skeletal muscle mass, function and regeneration.Mechanistic studies have focused on the loss of the receptor, with in vivo whole-body knockout models demonstrating reduced myofibre size and function and impaired muscle development.To understand the mechanistic role upregula